Harris blamed the City by the Bay’s $500 million budget deficit.
The staff laid off include three paralegals and two investigators.
The office had 253 total employees, including 123 lawyers, before the layoffs.
City Attorney Dennis Herrera and Public Defender Jeff Adachi have said that they have not had to lay anyone off for budget reasons. But they, like Harris, have cut vacant positions.
Kamala Devi Harris is the first female District Attorney to be elected in San Francisco, the first African American elected as District Attorney in California, and the first Indian American elected to the position in the US. She was cited by the New York Times to be among the seventeen most likely women to become the first female President of the United States.